DescriptionCapsule Networks have great potential to tackle problems in structural biology because of their attention to hierarchical relationships. This work describes the implementation and application of a capsule network architecture to the classification of RAS protein family structures on GPU-based computational resources. Our results show that the proposed capsule network trained on 2D and 3D structural encodings can successfully classify HRAS and KRAS structures. The capsule network can also classify a protein-based dataset derived from a PSI-BLAST search on sequences of KRAS and HRAS mutations. Experimental results show an accuracy improvement compared to traditional convolutional networks.